@article{S_J.K_I_L.M_J_P.W_2023, title={Acute insulin response following exercise and its association to lipid changes in sedentary African-American women}, volume={12}, url={https://ijpefs.org/index.php/ijpefs/article/view/489}, DOI={10.34256/ijpefs2315}, abstractNote={<p>Sedentary African-American (AA) women are at increased risk of hypertension, dyslipidemias, metabolic syndrome, and impaired insulin response to exercise. The purpose of the study was to determine the effects of a single bout of aerobic exercise on fasting serum insulin and glucose concentrations following 1464 kJ (350 kcal) of exercise and to determine if this response was associated with serum lipid concentrations in overweight AA women. Premenopausal AA women (n = 11, mean ± SD, age = 32.5 ± 4.8 yr., BMI = 29.8 ± 4.8 kg·m<sup>-2</sup>, % fat = 35.6 ± 6.3, VO<sub>2</sub>peak = 21.5 ± 3.6 ml·kg<sup>-1</sup>·min<sup>-1</sup>, total cholesterol = 4.8 ± 0.6 mmol·L<sup>-1</sup>, triglycerides = 0.60 ± 0.2 mmol·L<sup>-1</sup>, HDLC = 3.3 ± 0.5 mg·dL<sup>-1</sup>) performed 1464 kJ (350 kcal) of treadmill exercise at 60%-70%VO<sub>2</sub>peak. Fasting plasma insulin and glucose concentrations were collected 24-h prior to, and immediately, 24-h, and 48 h following exercise. Fasting insulin concentration increased immediately following exercise (Baseline=77.1 ± 10.42 vs. Immediately=117.4 ± 15.28 μU·mL<sup>-1</sup>, 95%CI= 32.71, 47.89; P<0.05). The change in insulin concentration from 24-h pre- to 24-h post-exercise was correlated with BMI (r= 0.51), VO<sub>2</sub>peak (r= -0.47), and the change in lipoprotein lipase activity (r=0.37) (<em>P</em><0.05 for all). In conclusion, in sedentary AA women, the insulin response immediately following exercise may be elevated, and is not suppressed below pre-exercise concentrations during the 48-h following exercise. The insulin response 24-h following exercise is modestly associated with markers of lipoprotein metabolism.</p>}, number={1}, journal={International Journal of Physical Education, Fitness and Sports}, author={S, Alhassan and J.K, Taylor and I, Rentería and L.M, Gómez-Miranda and J, Moncada-Jiménez and P.W, Grandjean}, year={2023}, month={Mar.}, pages={37–46} }